Bi-directional replication and random termination

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Bi-directional replication and random termination.

Two-dimensional (2D) agarose gel electrophoresis was used to study termination of DNA replication in a shuttle vector, YRp7', when it replicated in Escherichia coli, Saccharomyces cerevisiae and Xenopus egg extracts. In E. coli, the 2D gel patterns obtained were consistent with uni-directional replication initiated at a specific site, the ColE1 origin. In consequence, termination also occurred ...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2000

ISSN: 1362-4962

DOI: 10.1093/nar/28.10.2099